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Article on Rapid Mixer Granulator

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  Rapid Mixer Granulator (RMG) is a pharmaceutical machine that is used in the mixing and granulation of wet granules. It is a multi-purpose machine that performs both mixing and granulation functions in a single unit. The RMG is a very efficient machine that is widely used in the pharmaceutical industry due to its high mixing and granulation capabilities. The following is a diagram of a Rapid Mixer Granulator: The RMG consists of several key components, including: 1. Mixing Bowl: The mixing bowl is a cylindrical container where the mixing and granulation process takes place. It is made of stainless steel and is designed to withstand high pressure and temperature. 2.  Impeller: The impeller is a rotating blade that is located at the bottom of the mixing bowl. It is responsible for mixing the materials by creating a vortex motion in the bowl. The impeller also helps to break down the wet granules into smaller particles during the granulation process. 3. Chopper: The chopper is a high-sp

Types of Tablet Defect

Tablets are one of the most popular and widely used pharmaceutical dosage forms due to their ease of administration and accurate dosing. However, like any other pharmaceutical product, tablets can have defects that affect their quality, safety, and efficacy. In this article, we will discuss the causes, types, and prevention of tablet defects. Causes of Tablet Defects Tablet defects can occur due to various reasons, including: 1.  Formulation: The tablet formulation may not be properly designed, or the ingredients may not be mixed correctly, leading to defects in the final product. 2. Manufacturing process: The tablet manufacturing process may not be properly controlled, leading to defects such as improper tablet compression, improper coating, or improper drying. 3. Equipment: The tablet manufacturing equipment may not be properly maintained, leading to defects such as tablet chipping or breakage. 4. Environmental factors: Environmental factors such as temperature and humidity can af

Basic of Process Validation in Pharmaceutical Industry

  Process validation is an essential component of the pharmaceutical industry. It is a systematic approach to establishing documented evidence that a manufacturing process is capable of producing consistent and high-quality products that meet the required specifications. In this article, we will discuss the importance of process validation in the pharmaceutical industry, its stages, and its requirements. The Importance of Process Validation in the Pharmaceutical Industry The pharmaceutical industry is highly regulated, and it is essential to ensure that the products are manufactured consistently and meet the required specifications. Process validation is a critical step in this regard as it provides documented evidence that the manufacturing process is capable of consistently producing high-quality products. Process validation also helps in identifying the critical process parameters that affect the quality of the product. By identifying these parameters, it is possible to control them

Working Principle and Types of Tablet Compression Machine

The use of tablet compression machines has revolutionized the pharmaceutical industry by making it easier and more efficient to manufacture tablets in large quantities. These machines are used to compress a granulated powder into a solid tablet form, and they are an essential component of the tablet manufacturing process. In this blog post, we'll take a closer look at tablet compression machines and how they work.   The Working Principle of Tablet Compression Machines The working principle of a tablet compression machine involves a series of steps that start with the preparation of the granulated powder. The powder is fed into the machine through a hopper and is then transferred to the feeder system. The feeder system consists of a series of rollers that regulate the flow of the powder into the die cavity. The die cavity is the area where the compression takes place. The die is the tool that forms the tablet shape, and it is made up of two parts - the upper punch and the lower punc