Your Pharma Tech

Granulation is a crucial process in the pharmaceutical industry that involves the agglomeration of fine powder particles into larger, more easily manageable granules. Granulation is an essential process in the production of tablets and capsules, as it enhances the flow properties, compressibility, and uniformity of the final product. There are several granulation techniques used in the pharmaceutical industry, each with its advantages and disadvantages. In this blog, we will discuss some of the commonly used granulation techniques in the pharmaceutical industry. 1. Wet Granulation: Wet granulation is the most widely used granulation technique in the pharmaceutical industry. It involves the addition of a liquid binder to a dry powder blend, followed by agglomeration and drying. The liquid binder helps to bind the powder particles together to form granules. The most commonly used liquid binders are water, ethanol, and isopropanol. The wet granulation process can be divided into four stag

In the pharmaceutical industry, the drying of various materials is a critical process that is required to achieve the desired physical and chemical properties of the final product. One type of dryer that has gained popularity in recent years is the Fluidized Bed Dryer (FBD), which has become a preferred choice for many pharmaceutical manufacturers due to its efficiency, versatility, and ability to handle a wide range of materials. What is a Fluidized Bed Dryer? A Fluidized Bed Dryer is a type of dryer that uses gas or air to create a fluidized bed of particles that allows for efficient heat and mass transfer. In an FBD, the material to be dried is placed on a perforated tray or basket, which is then subjected to a high-velocity stream of hot gas or air. The velocity of the gas stream is high enough to cause the particles to become suspended in the air and form a fluidized bed. The particles are then exposed to the hot gas, which removes moisture and other volatile components, leaving b

  Rapid Mixer Granulator (RMG) is a pharmaceutical machine that is used in the mixing and granulation of wet granules. It is a multi-purpose machine that performs both mixing and granulation functions in a single unit. The RMG is a very efficient machine that is widely used in the pharmaceutical industry due to its high mixing and granulation capabilities. The following is a diagram of a Rapid Mixer Granulator: The RMG consists of several key components, including: 1. Mixing Bowl: The mixing bowl is a cylindrical container where the mixing and granulation process takes place. It is made of stainless steel and is designed to withstand high pressure and temperature. 2.  Impeller: The impeller is a rotating blade that is located at the bottom of the mixing bowl. It is responsible for mixing the materials by creating a vortex motion in the bowl. The impeller also helps to break down the wet granules into smaller particles during the granulation process. 3. Chopper: The chopper is a high-sp