Basics of Granulation Techniques
Granulation is a crucial process in the pharmaceutical industry that involves the agglomeration of fine powder particles into larger, more easily manageable granules. Granulation is an essential process in the production of tablets and capsules, as it enhances the flow properties, compressibility, and uniformity of the final product. There are several granulation techniques used in the pharmaceutical industry, each with its advantages and disadvantages. In this blog, we will discuss some of the commonly used granulation techniques in the pharmaceutical industry. 1. Wet Granulation: Wet granulation is the most widely used granulation technique in the pharmaceutical industry. It involves the addition of a liquid binder to a dry powder blend, followed by agglomeration and drying. The liquid binder helps to bind the powder particles together to form granules. The most commonly used liquid binders are water, ethanol, and isopropanol. The wet granulation process can be divided into four stag